Biochemical Changes in Epididymis following Treatment with Combined Extracts of Amaranthus Spinosus Roots and Dolichos Biflorus Seeds
نویسندگان
چکیده
Combined extracts of Amaranthus spinosus roots and Dolichos biflorus seeds at two different doses were administered to adult male rats to assess the structural and functional activity of epididymis. Biochemical studies were made throughout the experiment. Sperm motility was decreased markedly in the cauda epididymal fluid and the sperm counts were reduced in both caput and caudal segments. Epididymal weights, activities of acid and alkaline phosphatase and total LDH were decreased after high dose treatment in both the segments after 10 days of treatment. Protein concentrations were appreciably increased at both doses in the caput and at low dose only in the cauda segment. A reduction in sperm concentration was observed at both doses in cauda but only at high doses in caput. Thus, the herbal extracts impaired the structural and functional integrity of the epididymis.
منابع مشابه
Effects of Combined Extracts of Dolichos Biflorus Seeds and Amaranthus Spinosus Roots on the Accessory Sex Organs of Male Rats
Biological effects of extracts of Dolichos biflorus seeds and Amaranthus spinosus roots administered at two different doses (25 mg of D.biflorus seeds and 25 mg of A.spinosus roots; 50mg of D.biflorus seedsand 50 mg of A.spinosus roots) for 10 consecutive days were studied in the accessory sex organs of adult male rats. The observed adverse effect on organs weight, protein content and concentra...
متن کاملIn Vivo Psychopharmacological Investigation of Delphinium Denudatum and Amaranthus Spinosus Extracts on Wistar Rats
Introduction: In our modern era, life style of human being changes and updates every day that may affect their health status. There is an incredible expectation that natural origin drugs lack undesirable effects not like synthetic drugs, though have the same potency and efficacy. No scientific data is available about the antianxiety properties of Delphinium denudatum root and Amaranthus spinosu...
متن کاملEvaluation of Antihistaminic Activity of Dolichos Biflorus
Dolichos biflorus Linn. (FamilyFabaceae) is commonly known as ‘Horse gram’. The seeds are used in the treatment of piles, pain, constipation, wounds, urinary calculi, cough, edema, and asthma. The present study was therefore designed for evaluation of antihistaminic activity of seeds of Dolichos biflorus in the management of asthma. Antihistaminic activity of ethanolic extract of Dolichos biflo...
متن کاملBiological activity of Dolichos biflorus L. trypsin inhibitor against lepidopteran insect pests.
Protease inhibitors confer resistance in plants against insect pests by inhibiting larval gut proteases. Cultivars of Dolichos biflorus were screened for their inhibitory activity against midgut proteases of Pieris brassicae larvae. Seed extracts of developing and germinating seeds of HPK4 cultivar inhibited larval gut proteases of Spodoptera littoralis efficiently. Neonate larvae of P. brassic...
متن کاملDevelopment and Distribution of a Lectin from the Stems and Leaves of Dolichos biflorus.
The stems and leaves of the Dolichos biflorus plant contain a lectin that cross-reacts with antiserum against the seed lectin. This cross-reactive material (CRM) was followed during early seedling growth, stem elongation, and seed development using a specific radioimmunoassay.No CRM was detected in developing seeds, but very low levels were found in dormant and imbibed seeds. As germination pro...
متن کامل